Full Name: VRK Serine/Threonine Kinase 2
Genomic Location: Chromosome 2:57,907,629-58,159,920
Protein Size: 508 amino acids
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia.
- rs17190618 is linked to VRK2, it is located approximately 490,000 bases upstream.
- Population frequencies are approximately 90% for the reference allele (A) and 10% for the alternate allele (T).
- Studies suggest the A allele is associated with slightly reduced sleep duration.